The Office of Science operates 32 facilities that are available to the public on a competitive basis providing support to over 27,000 scientists, including graduate students and post-docs. Data rates at the user facilities are skyrocketing and will reach exabytes soon. Management, analysis and visualization of extreme-scale scientific data will undergo radical change during the coming decade. Coupled with changes in the hardware architecture of next-generation supercomputers, explosive growth in the volume of scientific data presents a host of challenges to researchers in computer science, mathematics and statistics, and application sciences. Failure to develop new data management, analysis and visualization technologies that operate effectively on the changing architecture will cripple scientific discovery and put national security at risk. With an emphasis on usability challenges and visualization, Dr. Nowell will explore the technical and scientific drivers and opportunities for data science research funded by the Advanced Scientific Computing Research program in the DOE's Office of Science. Dr. Nowell is a computer scientist and program manager in the Office of Advanced Scientific Computing Research (ASCR) within the Department of Energy’s Office of Science. She manages a broad spectrum of ASCR-funded computer science research, with a particular emphasis on scientific data management, analysis and visualization. She represents ASCR to the interagency Big Data Senior Steering Group and the Interagency Working Group on Human Computer Interaction and Information Management. She has also served as a research program manager for the National Science Foundation and the Department of Defense, managing a variety of programs related to the management and preservation of digital data, data integration and analysis, and scientific and information visualization. Dr. Nowell moved to ASCR in the spring of 2009 from Pacific Northwest National Laboratory, where she was a Chief Scientist in the Information Analytics group. She earned her Master of Science and Doctor of Philosophy degrees in Computer Science at Virginia Tech. She also has the Master of Fine Arts degree in Drama from the University of New Orleans and the Master of Arts and Bachelor of Arts degrees in Theatre from the University of Alabama.